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So what are some great movies about relationships that were powerful but didn't last? The only one that's coming to me right at the moment is The Man I Love, since I've seen it quite recently, but there's got to be more than that. I'm also not talking about the type of story where one of the lovers dies (e.g., Moulin Rouge or Titanic or more recently Bright Star). What I'm thinking of is stories where the romance dies out or doesn't quite work over time for whatever reason. Not necessarily downbeat, but bittersweet. There must be a zillion of them, but for some reason my mind is blanking. Maybe the recent Two Lovers? I didn't see that, but it sounded interesting.

Oh, right, Shakespeare in Love would be another one.

Updates, as I think of them (more suggestions in comments, of course):

Code 46 (a great movie) and Nine Songs (a terrible movie) by Michael Winterbottom.

Diva might fit too, although the relationship between the courier and the diva is perhaps not strong enough, more of a fling, even if an exultant one. [Although now that I've watched it yet again -- since writing the previous sentence -- I'm not sure where the relationship is going at the end of the film. More irresolve.]

La femme Nikita is another French genre film that fits the bill.

Choose Me is like Eternal Sunshine of the Spotless Mind in that it's specifically about the fragility of romantic relationships and ends on the (re)formation of one with a lot of uncertainty about whether it will last. It is irresolute.

Velvet Goldmine -- yeah, I like a lot of movies in this vein. No surprise. This one is a series of lapsed or momentary loves.